DNA methylation at CG sites is important for gene regulation and embryonic development.In mouse oocytes, de novo CG methylation requires preceding transcription-coupled histone mark H3K36me3 and is mediated by a DNA methyltransferase DNMT3A.DNMT3A has a PWWP domain, which recognizes H3K36me2/3, and heterozygous Jordan 7 mutations in this domain, in
Comparison of Functional Recovery in the Very Early Period After Surgery Between Plate and Nail Fixation for Correction of Stable Femoral Intertrochanteric Fractures
Purpose: This study aimed to compare the differences in functional recovery between patients undergoing plate and nail fixation in the very early period after surgery.Method: This study was designed as a controlled clinical trial that included 18 patients who were surgically treated with either dynamic hip screw as plate fixation or proximal femora
Blockchain trading mechanism based on attached chain for the delay tolerant network
In order to deploy a blockchain on the non-continuous connectivity delay tolerant network,a blockchain trading mechanism was designed,which could run on this type of network.First,the identifier Tip Cleaner was introduced into the existing block structure and a block structure on the attached chain was presented,which could append the blocks genera
Evidence of Criminal Acts of Origin in The Prevention and Eradication of Money Laundering Law Under Presumption of Innocence Principle
This study aims to determine the contradiction between the provisions on the proof of the original criminal act with the principle of Presumption of Innocence in the Anti-Money Laundering Law 2010.The research was conducted with normative SHAMPASTE research method using statutory approach, conceptual approach, historical approach, and historical ap
Towards a More Accessible Cultural Heritage: Challenges and Opportunities in Contextualisation Using 3D Sound Narratives
This paper reports on the exploration of potential design opportunities for social media and technology to identify issues and challenges in involving people in generating content within a cultural heritage context.The work is divided into two parts.In the first part, arguments are informed by findings from 22 in-depth semi-structured interviews t-